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5.363 Organic Structure Determination (New)

Prereq: 5.12; Coreq: 5.13
U (Fall; partial term)
4 Units. Partial Lab

Introduces modern methods for the elucidation of the structure of organic compounds. Students carry out transition metal-catalyzed coupling reactions, based on chemistry developed in the Buchwald laboratory, using reactants of unknown structure. Students also perform full spectroscopic characterization - by proton and carbon NMR, IR, and mass spectrometry of the reactants - and carry out coupling products in order to identify the structures of each compound. Other techniques include transfer and manipulation of organic and organometallic reagents and compounds, separation by extraction, and purification by column chromatography. Satisfies 4 units of Institute Laboratory credit.

R. L. Danheiser, J. Van Humbeck

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Chemistry and Biology (Course 5-7)

http://catalog.mit.edu/degree-charts/chemistry-biology-course-5-7/

General Institute Requirements (GIRs) The General Institute Requirements include a Communication Requirement that is integrated into both the HASS Requirement and the requirements of each major; see details below. Summary of Subject Requirements Subjects Science Requirement 6 Humanities, Arts, and Social Sciences (HASS) Requirement; at least two of these subjects must be designated as communication-intensive (CI-H) to fulfill the Communication Requirement. 8 Restricted Electives in Science and Technology (REST) Requirement [can be satisfied by 5.12 or 5.60 and 7.03 in the Departmental Program] 2 Laboratory Requirement (12 units) [can be satisfied by 7.02[J] or the combination of 5.351 , 5.352 , and 5.363 or 7.102 in the Departmental Program] 1 Total GIR Subjects Required for SB Degree 17 Physical Education Requirement Swimming requirement, plus four physical education courses for eight points. Departmental Program Choose at least two subjects in the major that are designated as communication-intensive (CI-M) to fulfill the Communication Requirement.

Chemical Engineering (Course 10)

http://catalog.mit.edu/degree-charts/chemical-engineering-course-10/

...of Enzyme Mutants , 5.362 Kinetics of Enzyme Inhibition , and 5.363 Organic Structure Determination...

Chemistry (Course 5)

http://catalog.mit.edu/degree-charts/chemistry-course-5/

General Institute Requirements (GIRs) The General Institute Requirements include a Communication Requirement that is integrated into both the HASS Requirement and the requirements of each major; see details below. Summary of Subject Requirements Subjects Science Requirement 6 Humanities, Arts, and Social Sciences (HASS) Requirement; at least two of these subjects must be designated as communication-intensive (CI-H) to fulfill the Communication Requirement. 8 Restricted Electives in Science and Technology (REST) Requirement [one subject can be satisfied by 5.12 , 5.60 , or 5.61 in the Departmental Program] 2 Laboratory Requirement (12 units) [can be satisfied from among 5.351 , 5.352 , 5.353 , and 5.363 in the Departmental Program] 1 Total GIR Subjects Required for SB Degree 17 Physical Education Requirement Swimming requirement, plus four physical education courses for eight points. Departmental Program Choose at least two subjects in the major that are designated as communication-intensive (CI-M) to fulfill the Communication Requirement.