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5.361 Expression and Purification of Enzyme Mutants (New)

Prereq: 5.07[J] or 7.05, 5.352 or 5.310 Coreq: 5.362
U (Spring; partial term)
3 Units

Students use biochemical techniques for protein expression and DNA manipulation of Bcr-Abl kinase, which is inhibited by the blockbuster drug Gleevec in the treatment of chronic myelogenous leukemia. Uses various standard bioanalytical and biochemical methods in lab to characterize and produce this protein.

B. Pentelute

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Chemical Engineering (Course 10)

http://catalog.mit.edu/degree-charts/chemical-engineering-course-10/

...4 Combination of 5.361 Expression and Purification of Enzyme Mutants , 5.362 Kinetics of...